What is Drontal Tablet? What is it used for, dosage and side effects.

What is Drontal Tablet?

Drontal Tablet is a broad-spectrum antiparasitic veterinary drug used in the treatment and control of internal parasites (helminths) in dogs and cats. Its primary purpose is to eliminate parasites such as roundworms and flatworms that inhabit the digestive system. Drontal Tablet is preferred both for the treatment of active infestations and as part of regular parasite control programs.

One of the most important features of Drontal Tablet in veterinary practice is its effectiveness against multiple parasite species simultaneously . This makes it possible to control complex infestations with a single product. Drontal Tablet stands out as an important treatment option, especially in young animals with high parasite loads, stray animals, or individuals who have not received regular preventative treatment.

Drontal Tablet is an orally administered product, and its tablet form generally makes administration easy . In most cases, a single dose or administration at intervals determined by the veterinarian is sufficient. The drug's effect is based on targeting the nervous and muscular systems of the parasites , causing paralysis and elimination from the body .

This product is available in different formulations and dosage options for both cats and dogs . Choosing the correct product based on breed, age, weight, and type of parasite is crucial. Using the wrong product or dose can lead to reduced effectiveness or unwanted side effects.

Drontal Tablet Active Ingredients and Mechanism of Action

The effectiveness of Drontal Tablet is based on the combined action of its multiple antiparasitic active ingredients. This combination targets the different biological structures of various parasite species, creating a broad spectrum of action.

Depending on the formulation of Drontal Tablet, the most common active ingredients are:

• Praziquantel

• Pyrantel embonate (or pyrantel pamoate)

• Febantel (in some dog formulations)

Each of these active ingredients has a different mechanism of action:

Praziquantel is particularly effective against flatworms (tapeworms) . It increases calcium permeability in the parasite's cell membrane, causing sudden muscle contractions followed by paralysis. This results in the parasite losing its ability to attach to the intestinal wall and being expelled from the body through the digestive system.

Pyrantel is most effective against roundworms and hookworms . It induces spastic paralysis by stimulating nicotinic acetylcholine receptors at the neuromuscular junction of the parasite. The paralyzed parasites rapidly lose their viability and are expelled through intestinal movements.

Febantel , after being metabolized in the body, transforms into active compounds that disrupt the parasite's energy metabolism. This effect stops the parasite's growth and reproduction, eventually leading to its death. Febantel is particularly effective against species such as hookworms and whipworms .

Drontal Tablets contain these active ingredients together:

• It provides simultaneous action against different types of parasites.

• It prevents treatments that might be insufficient on their own.

• It helps reduce the risk of parasites developing resistance.

Because the mechanism of action targets parasites directly, the risk of systemic toxicity in the host animal is low when used at the correct dose. However, caution is still advised in cases of overdose, in very young offspring, or in weak animals .

Drontal Tablet Usage Areas (Indications)

Drontal Tablet is used to treat and control internal parasites that infest the digestive system of dogs and cats. Its uses may vary depending on the type of parasite, the severity of the infestation, and the animal's living conditions. In clinical practice, Drontal Tablet is generally preferred as part of both therapeutic and preventative programs.

The main indications for Drontal Tablet are:

• Roundworm infestations (Toxocara spp., Toxascaris spp.) are particularly common in puppies and kittens. Symptoms may include abdominal distension, stunted growth, diarrhea, and vomiting.

• Hookworm infestations (Ancylostoma spp., Uncinaria spp.) are associated with anemia, weakness, and dark-colored stools. Drontal Tablet is an effective treatment option against these species.

• Whipworm infestations (Trichuris vulpis – in dogs) can manifest as chronic diarrhea, weight loss, and mucous stools. Formulations containing Febantel are effective against these parasites.

• Flatworm (tapeworm) infestations (Dipylidium caninum, Taenia spp.) occur especially after ingesting fleas. Thanks to its praziquantel content, Drontal Tablet is effective in eliminating tapeworms.

Drontal Tablet is preferred for its effectiveness in treating complex parasitic infestations, as it can be a standalone treatment. It offers a treatment option for multiple parasite species present simultaneously, eliminating the need for separate medications for each type.

Moreover:

• stray animals

• Shelter animals

• Pets that have not undergone a regular parasite treatment

In high-risk groups such as those mentioned, Drontal Tablets can also be used prophylactically at regular intervals. However, the frequency of prophylactic use must be determined by a veterinarian.

Drontal Tablet Parasite Cycle and Area of Activity

To properly evaluate the effectiveness of Drontal Tablet, it is necessary to understand the life cycle of the parasites it targets. Most internal parasites are expelled into the environment in egg or larval form, leading to reinfection under suitable conditions.

Roundworms and hookworms typically:

• Contaminated feces

• Dirty soil

• Infected game animals

• Through breast milk or placenta

The parasites infect the animal. They settle in the intestines, disrupting nutrient absorption and causing systemic effects.

Flatworms (tapeworms) are mostly:

• It is transmitted through an intermediate host (especially fleas ) . Therefore, using Drontal Tablets alone may not be sufficient; simultaneous external parasite control is of great importance.

Drontal Tablet's area of application:

• It is about adult parasites living in the intestinal lumen.

• It targets the nervous and muscular systems, preventing parasites from attaching.

• It allows paralyzed parasites to be expelled through bowel movements.

However, an important point is this: Drontal Tablet is not effective against parasite eggs . Therefore:

• If environmental contamination continues

• If the animal becomes reinfected

Repeat dose administrations may be necessary at specific intervals. This is especially common in young animals and in environments with many animals.

Unless the parasite cycle is broken, single-dose applications do not provide lasting protection. Therefore, Drontal Tablet:

• Environmental hygiene

• External parasite control

• Regular follow-up

It shows the highest effectiveness when used together with other products.

How to Use Drontal Tablets? (Step-by-Step)

The effectiveness of Drontal Tablets depends on the correct dosage and administration. Incorrect administration can lead to treatment failure and unnecessary side effects. Therefore, the following steps must be followed sequentially and carefully.

1. Determining the animal's correct weight: The animal's current weight must be measured before administration. Dosage calculations based on estimated weight are risky, especially for small breeds and puppies.

2. Choosing the Right Drontal Formula: Different Drontal tablet forms are available for cats and dogs. Also, some products are only targeted at specific types of parasites. Species, age, and the targeted parasite spectrum should be considered.

3. Oral administration of the tablet : Drontal Tablet is generally administered orally:

• By placing it directly into the mouth.

• Or with a small amount of food.

It can be administered. It is important to ensure the tablet is swallowed whole. If it is broken up and spat out or vomited, the administration will be considered unsuccessful.

4. Use with or without food: In most cases, Drontal Tablets can be used with or without food . However, in animals with gastric sensitivity, administering it after a light meal may improve tolerability.

5. Single dose or repeat dose decision: In many cases, a single dose is sufficient. However:

• High parasitic load

• baby animals

• Environments with a high risk of environmental contamination.

If necessary, a readjusted dose can be planned after 2-3 weeks under the supervision of a veterinarian.

6. Post-application observation: Within the first 24 hours:

• Vomiting

• Diarrhea

• Weakness

The animal should be observed for symptoms such as these. Mild and short-lived symptoms are usually temporary.

Drontal Tablet Preparation Before Use

Preparations made before administering Drontal Tablets both increase the drug's effectiveness and reduce the risk of side effects. This step is often overlooked, but it is critical for clinical success.

Assessment of the animal's general health status: In animals with fever, severe diarrhea, vomiting, or marked weakness, the general condition should be stabilized first. Antiparasitic treatment may be postponed in animals with severe systemic disease.

Age and physiological condition control: Dose sensitivity increases in very young puppies, elderly animals, or individuals in poor condition. Veterinary evaluation is mandatory in these groups.

Pregnancy and lactation: The use of Drontal Tablets in pregnant or lactating animals may not always be safe. The decision to use them must be made by a veterinarian.

Questioning about concurrently used medications : When certain medications are used together:

• It can increase the risk of side effects.

• It can create a metabolic load.

Therefore, all medications the animal is currently taking should be reviewed.

Assessment of environmental risk factors: Simply administering the medication is not enough. Before use:

• Cleaning the living area

• External parasite (especially flea) control

• Contact with other animals

This should be taken into consideration. Otherwise, re-infestation may develop again in a short time.

Owner information: To the animal owner:

• The purpose of the drug

• Possible side effects

• Observation period

It must be explained clearly. This will prevent unnecessary panic and incorrect interventions.

Drontal Tablet Dosage and Frequency of Administration

The dosage of Drontal Tablets is determined according to the animal's species, weight, and the product formulation used . The basic principle in dose calculation is to provide the correct amount of active ingredient according to weight . A low dose may lead to inadequate treatment, while a high dose may increase the risk of side effects.

Dosage in dogs (general principles): Drontal Tablet formulations for dogs are generally dosed according to specific weight ranges . The tablets are often divisible, and the number of tablets is increased as the weight increases. In cases suspected of whipworm (Trichuris), formulations containing febantel are preferred.

Dosage in cats (general principles): Drontal Tablets for cats are formulated for a lower dose. Cats have a lower tolerance to overdose compared to dogs; therefore, precise weight measurement is even more important.

Basic approaches to frequency of application:

• Treatment of active infestation: In most cases, a single dose is sufficient. However, if there is a high parasite load or high environmental risk, a booster dose may be needed after 2–3 weeks .

• In young animals: Initial treatments are usually performed at more frequent intervals. The risk of re-infestation is high because the immune system is not fully developed.

• Preventive use: In regular parasite control programs, the application interval is usually planned between 1–3 months . This interval varies depending on the animal's living conditions and contact with the external environment.

Key clinical points:

• Using more than one antiparasitic product simultaneously is generally not recommended.

• Dose repetitions should be done based on risk assessment , not out of "habit."

• Since it has no effect on parasite eggs, environmental control should not be neglected.

Differences Between Drontal Tablets and Similar Internal Parasite Medications

The following table has been prepared to compare Drontal Tablet with some commonly used internal parasite medications in veterinary medicine in terms of their range of action and application approach .

Product / Active Ingredient	Spectrum of Effect	Featured Feature	Irritability
Drontal Tablet	Roundworms, hookworms, whipworms*, tapeworms	Broad spectrum, combined effect.	It does not provide flea control.
Products containing milbemycin	Roundworms, some heartworms	Suitable for protective programs	Limited effect on tapeworms.
Pyrantel alone	Roundworms and hookworms	Sufficient for simple infestations.	Ineffective against tapeworms.
Praziquantel alone	Tapeworms	Strong, targeted impact.	Ineffective against roundworms.
Fenbendazole-based products	Broad spectrum of roundworms	Long-term treatment option	Limited effect on tapeworms.

* The effect on whipworms applies to formulations containing febantel.

Clinical evaluation: Drontal Tablet is advantageous because it provides broad coverage with a single product in cases where mixed infestations are common . However, if only a specific parasite is targeted, narrower-spectrum products may be preferred. Therefore, the "most suitable" product should be chosen, rather than the "strongest" one.

Important Considerations (Safety) When Using Drontal Tablets

Although Drontal Tablet is generally considered a safe antiparasitic product, as with all veterinary medicines, it should be used with caution in specific situations. Safe use depends not only on the drug itself, but also on the animal's general condition and environmental factors.

Overdosing should be avoided. Using Drontal Tablets in excessively high doses may lead to undesirable reactions, especially in small breeds and young animals. If the tablet is divided, ensure that the dose is correctly adjusted.

Weak and systemic diseased animals: In animals with severe infection, significant weight loss, fever, or metabolic disease, a risk-benefit assessment should be performed before antiparasitic treatment. Treatment may be postponed if necessary.

Repeated and uncontrolled applications should be avoided. Frequent and unjustified repetition of Drontal Tablets:

• Unnecessary drug burden

• Increased risk of side effects

• False sense of security in parasite control.

This could be the reason. Regular use must be planned.

Simultaneous external parasite control should not be neglected. Unless fleas, which are intermediate hosts for tapeworms, are controlled, Drontal Tablet application will not provide a permanent solution. Internal and external parasite control should be addressed together.

Precautions regarding human contact: Hands should be washed after tablet administration. Direct contact with the medication should be avoided, especially for children and vulnerable individuals.

Veterinary consultation is recommended , even for routine use, especially:

• If it will be used for the first time

• If there is any doubt about the animal's health condition

• If there is a history of side effects

Seeking the opinion of a veterinarian increases safety.

Drontal Tablet Side Effects and Possible Reactions

Drontal Tablet is well tolerated in most animals. However, some individuals may experience mild and transient side effects, especially after the first administration. These effects are generally related to the death and elimination of parasites from the intestines, rather than the drug itself.

Common mild side effects may include:

• Short-term fatigue

• Anorexia

• Soft stools or mild diarrhea

• Vomiting is rare.

These symptoms usually resolve spontaneously within 24 hours and do not require any special intervention.

Less common reactions:

• Marked lethargy

• Severe vomiting or diarrhea

• Excessive salivation

• Behavioral changes

In such cases, the medication should not be repeated and a veterinarian should be contacted.

Allergic reactions (very rare):

• Swelling in the face or lips

• Itching

• Difficulty breathing

These symptoms require immediate attention, and the medication should be discontinued completely.

Factors that increase the risk of side effects:

• Overdose

• Very young or very old animals

• Poor physical condition

• Simultaneous use of other medications

Although most side effects are temporary and mild , it is important for the animal owner to carefully observe the animal for the first 24–48 hours after application.

Can Drontal Tablets be used in young, pregnant, or lactating animals?

The use of Drontal Tablet in young, pregnant, and lactating animals requires special consideration . Drug tolerance may differ in these groups compared to adult and healthy individuals.

Use in young animals: Puppies and kittens are the most susceptible group to internal parasite infestations. However, their dose sensitivity is high because their metabolic systems are not fully developed. Drontal Tablet:

• It should not be used below a certain minimum age and weight limit.

• In young animals, the procedure must be performed based on weight and under the supervision of a veterinarian.

When used at the right time and in the right dose, it plays an important role in preventing parasite-related growth retardation and digestive problems in offspring.

Use in pregnant animals: The use of antiparasitic drugs during pregnancy should always be considered with caution. While some formulations of Drontal Tablet may be used during certain periods of pregnancy, their use is generally not recommended, especially in the early stages of pregnancy . During this period:

• Because fetal development is delicate

• The project should not be implemented without a risk-benefit assessment.

Whether or not its use is necessary in the later stages of pregnancy should be decided by a veterinarian.

Use in lactating animals: During lactation, some active ingredients may pass to offspring through milk. Use of Drontal Tablets:

• The age of the cub

• Breastfeeding period

• The formulation used

This should be considered during the evaluation process. Routine use is not preferred unless deemed necessary.

Situations Requiring Veterinary Approval for the Use of Drontal Tablets

In some cases, self-administration of Drontal Tablets is not appropriate and requires veterinary approval . This is important to prevent potential complications.

The main situations requiring veterinary approval are as follows:

• Puppies younger than 6 weeks old

• Pregnancy or breastfeeding period

• Significant weight loss or poor physical condition

• Presence of severe diarrhea, vomiting, or fever

• History of liver or metabolic disease

• Previous reaction to antiparasitic drugs

• Using multiple medications at the same time

Moreover:

• If the type of parasite is unclear

• If there are recurrent infestations

• If no clinical improvement is observed despite treatment

A diagnosis-based approach should be preferred over routine procedures.

Veterinary approval is important not only for safety reasons, but also for selecting the most appropriate product and preventing unnecessary medication .

Drontal Tablet Post-Application Follow-up and Efficacy Monitoring

After the administration of Drontal Tablets, the success of the treatment is evaluated not only by the administration of the drug but also by post-administration follow-up . In the first 24–48 hours, the animal:

• General situation

• Appetite

• Stool structure

It should be observed from this perspective.

It is normal for parasites to be expelled in the stool, and this usually indicates that the treatment is effective. However:

• If symptoms persist

• If parasites are seen again in the stool

• If clinical symptoms do not improve

A booster dose or a different treatment protocol may be required.

In the long term:

• Regular check-ups

• Environmental hygiene

• External parasite control

When administered together, Drontal Tablet provides a high success rate in controlling internal parasites.

Frequently Asked Questions

What is Drontal Tablet used for?

Drontal Tablet is a broad-spectrum antiparasitic product used for the treatment and control of internal parasites living in the digestive system of dogs and cats. It is effective against roundworms, hookworms, whipworms, and in some formulations, tapeworms. It is used both in the treatment of active infestations and in regular internal parasite control programs.

Which parasites is Drontal Tablet effective against?

Drontal Tablet is effective against parasites such as Toxocara, Toxascaris, Ancylostoma, Uncinaria, Trichuris (depending on the product content), and Dipylidium. Its ability to provide broad coverage with a single product is a significant advantage in cases where multiple parasites are present simultaneously.

How is Drontal Tablet used in dogs?

In dogs, it is administered orally. The tablet can be swallowed directly or concealed in a small amount of food. The dose is determined according to the dog's weight. In most cases, a single dose is sufficient, but a repeat dose may be prescribed if deemed necessary by the veterinarian.

Is Drontal Tablet safe for cats?

When the correct dosage and cat-specific formulation are used, it is generally safe. Since cats are more susceptible to overdose than dogs, weight measurement and product selection are crucial. Products intended for dogs should not be used on cats.

Can Drontal Tablets be used in young animals?

It can be used under veterinary supervision in puppies above a certain minimum age and weight limit. Very young, weak, or poorly healthy puppies must be evaluated before use.

Can Drontal Tablet be used in pregnant animals?

Use during pregnancy always requires caution. It is generally not recommended, especially in the early stages of pregnancy. The decision to use should be made by a veterinarian, taking into account the stage of pregnancy and the animal's condition.

Is Drontal Tablet safe in lactating animals?

During lactation, some active ingredients can pass to offspring through breast milk. Therefore, instead of routine use in lactating animals, action should be taken only on the recommendation of a veterinarian.

Should Drontal tablets be given on an empty stomach or with food?

Generally, there is no significant difference between administering it on an empty stomach or after a meal. However, in animals with sensitive stomachs, administering it after a light meal may reduce the risk of side effects.

How many days does it take for Drontal tablets to take effect?

Parasites become inactive and begin to be expelled in the feces within 24–48 hours after application. The duration of effect may vary depending on the parasite load and the general condition of the animal.

Does Drontal Tablet kill parasite eggs?

No. Drontal Tablets are effective against adult parasites, not eggs. Therefore, environmental cleanliness and, if necessary, repeat dosing the dose are important.

Is it normal to find parasites in stool after taking Drontal tablets?

Yes, it is normal to excrete dead or immobile parasites in the stool after treatment, and this indicates that the medication is effective.

What are the side effects of Drontal Tablet?

The most common side effects are mild and temporary. Short-term fatigue, loss of appetite, soft stools, or mild diarrhea may occur. In most cases, these resolve spontaneously within 24 hours.

Does Drontal tablet cause vomiting?

Some animals may experience vomiting, especially shortly after administration. In cases of severe or repeated vomiting, a veterinarian should be consulted.

Does Drontal Tablet cause allergic reactions?

Although very rare, allergic reactions can occur. Symptoms such as facial swelling, intense itching, or difficulty breathing require immediate attention.

When should Drontal tablets be prescribed again?

Booster doses depend on the severity of the infestation and environmental risks. A booster dose may generally be needed after 2–3 weeks. For prophylactic use, intervals are longer.

Should external parasite medication be used together with Drontal Tablet?

Yes. Controlling fleas, which are intermediate hosts for tapeworms in particular, is very important. The risk of re-infestation is high if external parasite treatment is not provided.

Do I need to use Drontal tablets every month?

Monthly use is not necessary for every animal. The frequency of use should be determined according to the animal's living conditions, exposure to the external environment, and risk of parasites.

Can Drontal Tablet be used in weak animals?

Caution should be exercised with animals that are extremely thin or in poor general condition. Their overall health should be assessed first.

Can Drontal Tablet be used with other medications?

It can be used with most medications, but if multiple medications are being used simultaneously, it is recommended to consult a veterinarian.

Does Drontal Tablet harm people?

This medication is for animals only. Hands should be washed after application, and children should be kept away from the medication.

Is Drontal Tablet sufficient for all internal parasites?

No. Different treatments may be necessary for certain types of parasites or in specific cases. Product selection based on diagnosis is important.

Is Drontal Tablet used for preventative or therapeutic purposes?

It can be used for both therapeutic and preventative purposes. The intended use determines the frequency of application.

Why does Drontal Tablet become re-infested?

Eggs in the environment, lack of hygiene, and failure to control external parasites can lead to re-infestation.

Are Drontal tablets suitable for all dogs and cats?

Suitable for most healthy dogs and cats, but special evaluation is required for puppies, pregnant or sick animals.

What precautions should be taken after taking Drontal tablets?

The animal should be observed for the first 24–48 hours, signs of side effects monitored, and environmental hygiene maintained.

Sources

• European Medicines Agency (EMA)

• Merck Veterinary Manual

• Bayer Animal Health Product Information