FeLV (Feline Leukemia) in Cats – Symptoms, Diagnostic Methods, Transmission Risks, and Long-Term Management Guide
- VetSağlıkUzmanı

- Nov 23
- 20 min read
What is FeLV (Feline Leukemia) in Cats?
FeLV (Feline Leukemia Virus) in cats is a serious and widespread retroviral infection that directly affects cats' immune systems , blood cells, and organ functions. While FeLV belongs to the same retrovirus family as immune-impacting viruses like FIV, its mechanism of action and clinical outcomes are much more aggressive . The disease can present with immunosuppression, anemia , tumor formation such as lymphoma, and numerous secondary infections.
Once inside the body, the FeLV virus invades bone marrow cells and immune system tissues. This disrupts the normal production of red blood cells, white blood cells, and platelets. As a result, cats become extremely susceptible to a variety of diseases. The problems seen in FeLV-positive cats are not due to the viral infection itself, but rather to the dramatic damage the virus inflicts on the immune system .
FeLV is specific to cats. It is not contagious to humans, dogs, or other animal species. It poses no risk to other animals living in the same household. However, it is one of the most dangerous infectious diseases for cats that wander outdoors or come into close contact with other cats.
The importance of this virus stems not only from its mortality risk but also from its ability to trigger a variety of clinical diseases. Depending on the stage of infection, FeLV can cause a variety of health conditions in cats:
Immunosuppression (immunosuppression)
Chronic infections
Anemia and hematological disorders
Lymphoma and other tumors
Reproductive disorders
For all these reasons, FeLV is considered one of the most important infectious viral diseases in veterinary medicine.

Types of FeLV in Cats
FeLV infection does not progress uniformly in every cat. The virus's behavior can vary depending on the cat's immune response, age, health, viral load, and duration of exposure. Therefore, FeLV is classified into several distinct clinical forms. This classification is crucial for determining both the course of the disease and the treatment approach.
1. Abortive Infection (Complete Overcoming of the Virus)
In this case, the cat encounters the virus, but because its immune system is strong, it stops the virus from multiplying at an early stage.
The cat will not become infected.
It is never FeLV positive.
In this case, it is thought that the cat develops a natural resistance to FeLV in the future.
Although this form is rare, it can occur in cats with strong immune systems, especially those exposed to the infection at a young age.
2. Regressive Infection (Silent Carriage)
The virus enters the body and multiplies for a while, but the immune system only partially controls the virus.
The cat may test positive initially.
After some time, FeLV tests may become negative.
However, viral DNA can persist in some tissues as a silent (latent) entity.
These cats may become positive again in the following years, which is very unlikely.
3. Progressive Infection (Active, Destructive Infection)
It is the most serious and dangerous form.
The virus multiplies uncontrollably.
Blood and tissues often test persistently positive for FeLV.
The immune system deteriorates rapidly.
The risk of tumors, anemia and opportunistic infections is very high.
In cats with this form, progression is rapid and aggressive.
4. Focal / Atypical Infection
In this form, the virus is concentrated in certain tissues, not throughout the system.
There may be limited infection in the spleen, lymph nodes, breast tissue, or gastrointestinal tract.
Blood tests can sometimes be negative and sometimes low positive.
The disease course is highly variable and diagnosis can be difficult.
5. FeLV Subgroups (Subtypes A, B, C, and T)
There are four main genetic variants of FeLV, each with different effects:
FeLV-A (Basic Form)
Found in all FeLV-positive cats.
It forms the basic building block for the formation of other variants.
FeLV-B
It occurs by mutation of form A.
It is associated with tumor (especially lymphoma) formation.
FeLV-C
It causes severe aplastic anemia.
It is rare but can be fatal.
FeLV-T
It targets T-lymphocytes.
It accelerates the collapse of the immune system.
Each subtype can lead to different clinical outcomes in cats, and therefore, although FeLV appears to be a single disease, it is actually a multifaceted, complex viral entity.

How is FeLV Transmitted in Cats?
FeLV (Feline Leukemia Virus) is one of the most easily transmitted viral diseases in cats. Its retroviral nature allows it to spread rapidly through both blood and body fluids. Understanding the disease's transmission mechanism is critical for both managing infected cats and protecting healthy cats.
FeLV has a wider range of transmission routes than other viral diseases; it can spread easily not only through bites but also through prolonged close contact.
1. Transmission through saliva (Most Common Way)
FeLV is found in high concentrations in the saliva of an infected cat. Transmission can occur through:
Cats licking each other
Shared use of food and water bowls
Sharing the same toys by mouth contact
Close social contact
Therefore, FeLV can spread rapidly in social cats , especially in crowded households or colony settings.
2. Contamination through Blood and Body Fluids
Blood contact carries high contagiousness:
Deep bite wounds
Bloody wounds
Nail and tooth blows during a fight
While FIV is mostly transmitted through bites, for FeLV even social contact may be sufficient for transmission .
3. Mother-Offspring Transmission (Vertical Spread)
It is one of the most dangerous ways FeLV is transmitted. A mother cat can transmit the virus to her kittens by:
via the placenta during pregnancy
During birth
Through milk during breastfeeding
The mortality rate is high in offspring of infected mothers.
4. Contamination through Nose and Eye Discharge
FeLV can also be found in nasal secretions.
Cats sniffing each other
Close contact
Use of shared beds or blankets
may facilitate virus transmission through nasal contact.
5. Weak Transmission Through Urine and Feces
These fluids may contain viruses, but their contagiousness is much lower than saliva. However, the risk may increase in cases of intense contact or poor hygiene conditions.
6. Shared Litter Box Use
Although the possibility of FeLV being transmitted through feces and urine is low, it is not completely zero. In multi-cat households, attention should be paid to litter hygiene.
7. Environmental Durability
FeLV does not survive long in the environment:
Inactivates within a few hours on dry surfaces
Sensitive to temperature changes
Easily destroyed with simple disinfectants such as bleach
However, continuous close social contact is usually sufficient for transmission.
Breeds at Risk for FeLV in Cats (Table)
There is no inherent predisposition to FeLV in certain breeds; risk is entirely related to lifestyle , outdoor habits , colony living , immune system , and stress levels . However, behavioral characteristics may increase the risk in some breeds.
The table below has been prepared in accordance with our standard in the format Disease Name | Description | Susceptibility Level (Low – Medium – High) :
Race | Explanation | Level of Predisposition |
The majority of the stray population is in this group. They go outside and have frequent contact with other cats. | A lot | |
Social, active, and curious about the outside world; may have a high tendency to escape. | Middle | |
Due to their large and strong structure, aggression may increase during a fight, increasing the risk in the external environment. | Middle | |
Bengal | It is a high energy breed, open to exploration, and may be prone to going out. | Middle |
They are calm cats that tend to live indoors; outdoor contact is generally low. | Little | |
Persian (Persian Cat) | They are one of the breeds that live in a home environment and have little contact with the outside world. | Little |
Due to its hairless structure, it is vulnerable in the outdoor environment; it is generally a house cat. | Little | |
Norwegian Forest Cat | Because it is a breed that loves the outdoors and has a high energy level, the risk may increase slightly. | Middle |

FeLV Symptoms in Cats
FeLV (Feline Leukemia Virus) causes a wide range of symptoms in cats. This is because the virus targets both the immune system and the bone marrow. Because FeLV infection weakens the cat's immune system, symptoms can be subtle or sudden. Symptoms vary depending on the type of infection, the cat's age, any concomitant infections, and the rate of progression.
1. Immunosuppression-Related Symptoms (Most Common Group)
Immunosuppression is the primary effect of FeLV.
Recurrent respiratory tract infections
Frequent sneezing, runny nose, eye discharge
Oral infections, stomatitis and gingivitis
Chronic skin infections
Prolonged non-healing wounds
These symptoms often respond temporarily to antibiotics but then recur shortly thereafter. This "relapse cycle" is typical of FeLV.
2. Symptoms of Anemia
Because FeLV specifically affects the bone marrow, anemia is common.
Pale gums
rapid breathing
Don't get tired easily
Anorexia
Whitening of the nail beds
Weakness and collapse
The FeLV-C variant can cause severe aplastic anemia and the clinical picture is more severe.
3. Lymph Node Enlargement
Another common symptom of FeLV infection is:
Lymph node enlargement in the neck, under the chin, armpit, and groin areas
This reflects both viral activity and immune suppression.
4. Gastrointestinal Symptoms
Intestinal infections occur more frequently in FeLV-positive cats.
Chronic diarrhea
Periodic vomiting
Stomach ache
Nutrient malabsorption
Frequent intestinal problems in FeLV-positive cats are indicative of immunodeficiency.
5. Weight Loss and Deconditioning
As the virus progresses, cats begin to lose muscle and fat tissue.
Slow but steady weight loss
Muscle wasting (especially in the hind legs)
Coarse and dull feather structure
This is one of the most obvious signs of progressive FeLV infection.
6. Tumor and Cancer Symptoms
The FeLV B variant is particularly associated with the development of lymphoma .
Abdominal mass formation
Difficulty breathing (if there is a mass in the chest)
Weight loss and loss of appetite
Weakness
Major differences in lymph nodes
FeLV is known to be the most common cause of cancer in cats.
7. Reproductive System Disorders
In FeLV-positive female cats:
Miscarriage
Birth of weak puppies
Sterilization problems
In men, there may be a decrease in sperm quality.
8. Neurological Symptoms
In advanced cases of FeLV, the following may be observed:
Balance disorders
Weak muscle control
Head tilt
Behavioral changes
9. General Symptoms
Fever attacks
Depression and fatigue
Drinking too little water or drinking too much water (due to accompanying kidney problems)
Playing less, withdrawing
Because the symptoms of FeLV are so diverse, laboratory tests play a critical role in diagnosis.
How Is FeLV Diagnosed in Cats?
Diagnosing FeLV is a multi-step process that includes both screening and confirmatory testing. No single symptom or single test is sufficient to make a definitive diagnosis. Therefore, modern veterinary medicine utilizes a multi-testing approach.
1. Clinical Examination
The veterinarian will first perform a thorough physical examination of the cat:
Checking the lymph nodes
Oral and gingival evaluation
Weight and muscle condition
Hair and skin condition
Respiratory and circulatory findings
Clinical examination raises suspicion of FeLV but does not provide a definitive diagnosis.
2. ELISA Rapid Test (Screening Test)
It is the first method used in the diagnosis of FeLV.
It is done with a few drops of blood.
It gives results within 10–15 minutes.
It detects FeLV antigen (p27).
Advantages: Fast, easy, economical Disadvantages: May cause false positives or false negatives.
3. Confirmation Test – IFA (Immunofluorescent Antibody Test)
It is performed on cats that are ELISA positive.
It has a higher accuracy rate.
It indicates the presence of infection in the bone marrow.
If it is positive, it indicates that the infection is advanced and persistent.
4. PCR Test (Viral DNA / RNA Diagnosis)
It is one of the most sensitive methods in the diagnosis of FeLV.
It directly detects the genetic material of the virus.
It can be used in both early and latent infections.
It can even reveal regressive infections.
PCR testing is particularly valuable in cats where ELISA is negative but there is clinical suspicion.
Hematological disorders due to FeLV may present as follows:
Anemia (especially macrocytic anemia)
Leukopenia (low white blood cell count)
Thrombocytopenia
CBC shows the effect of infection on immunity and bone marrow.
6. Biochemistry Tests
In FeLV positive cats:
Liver enzymes may be elevated
Protein levels may vary
Kidney functions may be impaired
These tests are necessary to identify complications.
7. Radiography and Ultrasound
If there is a suspected tumor or organ enlargement:
Ultrasound
Chest radiography
Abdominal scan
FeLV-associated lymphoma can form masses in the chest or abdomen.
8. Bone Marrow Aspiration
It may be necessary in severe anemia or advanced infections.
It indicates whether there is bone marrow suppression.
Important in evaluating the effects of the FeLV-C variant.
9. Testing Protocol for Kittens
Kittens do not receive antigens, but antibodies, from a FeLV-positive mother, so:
FeLV tests are more reliable.
Testing can be done between 8 and 12 weeks of age.
In doubtful cases, retesting after 1–3 months is recommended.
Diagnosis of FeLV is always made through multiple testing and clinical evaluation.
FeLV Treatment Methods in Cats
There is currently no definitive treatment for FeLV (Feline Leukemia Virus) that completely eradicates the virus; however, modern veterinary medicine has developed comprehensive management protocols that allow FeLV-positive cats to live many years of quality, healthy life. FeLV treatment is based on three primary goals:
Keeping the immune system strong,
Treat secondary infections quickly,
To control tumor growth and bone marrow suppression.
Below, all scientific and clinical methods related to FeLV treatment are explained in the most comprehensive way.
1. Immune System Supporting Treatments
Because FeLV directly targets the immune system, immune support therapy is the most important step.
A. Immunomodulators
It ensures the balanced functioning of the immune system.
Interferon-alpha low-dose protocols
Feline interferon (licensed in some countries) These drugs can reduce the frequency of infection by reducing the effects of the virus.
B. Antioxidant Supplements
Antioxidants strengthen cellular defenses:
Omega-3 fatty acids
Vitamin E
Taurine supplements
Lutein and coenzyme Q10 supplements
These supplements enhance the general well-being of FeLV-positive cats.
2. Treatment of Secondary Infections
The most common problem that FeLV positive cats face is recurrent infections due to immunodeficiency.
A. Treatment of Bacterial Infection
Broad-spectrum antibiotics
Antibiotic selection based on culture in resistant cases
Oral and dental treatments for infection control
B. Respiratory Tract Infections
Steam inhalations
Antibacterial or antiviral supplements
Nasal solutions
C. Skin Infections
Antiseptic baths
Antifungal treatments
Keeping wounds clean
Early intervention is vital because infections with FeLV can progress rapidly.
3. Management of Anemia and Bone Marrow Suppression
FeLV-C can cause particularly severe aplastic anemia .
Treatment options:
Vitamin B12 injections
Folic acid supplements
Blood transfusion (in severe anemia)
Bone marrow support treatments
Erythropoietin-like drugs (under veterinary control)
4. Treatment of Oral and Dental Diseases
Chronic stomatitis is very common in FeLV-positive cats.
Dental tartar cleaning
Pain management
Anti-inflammatory drugs
Extraction of problematic teeth if necessary
These treatments reduce the cat's pain and make feeding easier.
5. Tumor (Lymphoma) Treatment
FeLV-positive cats have an increased risk of developing lymphoma.
Treatment options:
Chemotherapy protocols
Steroid therapy
Supportive care
Some FeLV-positive cats may respond quite well to chemotherapy.
6. Nutrition and Metabolic Support
Foods containing high-quality protein
Additional water and calorie support with wet food
Easily digestible carbohydrates
Antioxidant-rich ingredients
In FeLV-positive cats, nutritional quality directly affects the course of the disease.
7. Lifestyle Adjustment
The cat should be kept at home (not allowed outside)
A stress-free, calm living space should be provided.
Clean water and hygienic sand environment should be provided.
Regular parasite protection should be carried out
These environmental factors greatly increase the success rate of treatment.
8. Regular Clinical Control
A FeLV positive cat should be checked every 3–6 months:
CBC
Biochemistry
Lymph node examination
Oral control
Kilogram and condition tracking
Early diagnosis and early treatment are the most important factors that prolong life.
Complications and Prognosis if FeLV is Left Untreated in Cats
If FeLV is left untreated or improperly managed, the disease gradually weakens the cat's immune system, leading to numerous serious complications. Many of these complications significantly reduce quality of life and can be fatal.
1. Severe and Recurrent Infections
Due to immunosuppression in FeLV positive cats:
Respiratory tract infections
Skin infections
Oral infections
Eye infections
Urinary tract infections
frequently recurs and becomes resistant to treatment.
2. Severe Anemia and Blood Disorders
Because FeLV suppresses bone marrow:
Severe anemia
Low platelet count
Tendency to bleeding
Weakness and collapse
FeLV-C, in particular, can cause lethal anemia.
3. Lymphoma and Other Tumors
It is one of the most important complications associated with FeLV.
Mediastinal lymphoma (mass in the chest cavity)
Multicentric lymphoma
Gastrointestinal lymphoma
These tumors cause breathing difficulties, abdominal distension, loss of appetite and weight loss in cats.
4. Chronic Stomatitis and Oral Diseases
Inflammation in the mouth makes eating very difficult:
Pain
Bad breath
Drooling
Avoiding food
If left untreated, it will cause severe weight loss and dehydration in the cat.
5. Reproductive Problems
In FeLV-positive female cats:
Low
Stillbirth
Birth of weak puppies
In men, sperm production may decrease.
6. Organ Enlargements and Failures
Due to widespread immunosuppression:
Liver enlargement
Spleen enlargement
Kidney dysfunction
may occur.
7. Neurological Disorders
In some cases of FeLV:
Loss of balance
Coordination disorder
Behavioral changes
Hind leg weakness
symptoms such as may develop.
8. Life Expectancy and Prognosis
The prognosis for FeLV-positive cats is variable:
In abortive/regressive infections, the cat can live long and healthy lives.
Survival in progressive FeLV infection may vary between 2 and 5 years.
Quality home care, stress reduction, and early treatment greatly prolong life.
Although FeLV is considered fatal, with proper management, many cats can live stable and happy lives for many years.
Home Care and Prevention Methods for FeLV Positive Cats
The lifespan and quality of life of FeLV-positive cats are strongly dependent on the quality of care provided at home. Because FeLV weakens the immune system, the home environment should be a safe haven for the cat and should be designed to minimize the risk of infection. Below are the most comprehensive home care protocols for FeLV-positive cats.
1. Strictly Living at Home
Letting FeLV-positive cats outside poses serious risks:
The possibility of infection from stray cats
Risk of injury and new viral load as a result of fighting
Environmental stress and cold-heat effects
The emergence of situations that will delay medical intervention
Staying indoors significantly prolongs the lifespan of FeLV-positive cats.
2. A Hygienic and Orderly Living Space
Hygiene is critical for cats with low immunity:
Food and water bowls should be washed every day.
The litter box should be cleaned at least once a day and the litter should be changed weekly.
Bedding, blankets and cat items should be washed regularly.
The house should be kept free from dust and mold.
As hygiene increases, the risk of secondary infection decreases.
3. Minimize Stress
FeLV-positive cats become ill more quickly under stress.
An environment away from noise and crowds should be provided.
A fixed daily routine should be implemented at home.
A safe corner should be created where the cat can hide.
Sudden changes in the home should be avoided.
Stress is one of the strongest factors that suppresses immunity.
4. Quality Nutrition Program
FeLV positive cats may have a weakened metabolism, so their feeding plan should be chosen with care.
High-quality, easy-to-digest protein sources
Foods rich in omega-3 fatty acids
A diet dominated by wet food
Antioxidant-containing foods
Veterinarian-approved nutritional supplements if necessary
Nutrition is one of the most critical elements in managing FeLV.
5. Encouraging Water Consumption
FeLV-positive cats may be at increased risk of dehydration.
Daily fresh water
Increasing the desire to drink water with water fountains
Additional fluid support with wet food
Water consumption is vital for kidney health.
6. Protecting Oral and Dental Health
One of the most common and problematic complications of FeLV is oral diseases (stomatitis).
Bad breath and drooling should be closely monitored.
If necessary, oral care gels and veterinarian-approved products can be used.
Soft wet food reduces mouth pain.
Early treatment of oral diseases makes feeding easier.
7. Not to Disrupt Parasite Control
Parasites are a source of serious infection for FeLV-positive cats.
Monthly external parasite protection
Regular internal parasite treatment
Keeping the home environment clean
Parasite control is essential for maintaining immunity.
8. Regular Weight and Hair Monitoring
Weekly weighing
Tracking hair loss or matting
Checking for lesions on the skin
These small checks provide insight into the rate of progression of FeLV.
9. Daily Monitoring of Disease Symptoms
In FeLV-positive cats, symptoms can change rapidly.
Decreased appetite
Excessive sleepiness or fatigue
Respiratory distress
Diarrhea
Redness in the mouth
Eye discharge
If every change is noticed early, the success rate of treatment increases.
Owner Responsibilities in FeLV Positive Cats
The most important factor in improving the quality of life of an FeLV-positive cat is the conscientious, regular, and attentive care provided by the cat's owner. FeLV management is not just about medication; owner behavior is an integral part of the treatment process.
1. Never Skip Regular Veterinary Checkups
FeLV-positive cats should undergo a full clinical examination every 3–6 months.
Blood tests (CBC, biochemistry)
Oral and dental examination
Evaluation of lymph nodes
Organ ultrasounds (when necessary)
Weight and fitness tracking
Early detection = long life.
2. Use Medication and Supplements Regularly
Antibiotics, antivirals or immunomodulators should be given regularly and in the correct dose.
Supplements (Omega-3, vitamins, antioxidants) should be applied under veterinary supervision.
Drug therapy should not be stopped early.
Disorder accelerates immune suppression.
3. Minimizing Stress Sources at Home
Avoid loud noises, crowds, and sudden movements
Making the process of adding new animals very slow
Creating a special safe space for your cat
FeLV-positive cats become ill much more easily under stress.
4. Monitor Nutrition Closely
The food bowl should be checked daily.
If there is a loss of appetite, immediate intervention should be made.
Symptoms of mouth pain should be observed while eating.
New food changes should only be made with veterinary approval.
5. Managing Contact with Other Cats
The risk of transmission of FeLV is higher than that of FIV. Therefore:
FeLV positive cats should be kept separate from healthy cats if possible.
If they live in the same house, the risk of fighting should be zero.
Food, water and litter trays can be separated.
Good management of this balance by the owner prevents the spread of FeLV.
6. Recognizing Disease Symptoms
The owner should be aware of the early signs of FeLV:
Sudden weight loss
Oral problems
Respiratory changes
Eye and nose discharge
Low energy
Dullness in feathers
These symptoms can progress rapidly.
7. Do Not Neglect Oral and Dental Care
This is one of the areas where FeLV positive cats have the most difficulty.
Bad breath
Redness in the mouth
Drooling
Pain while eating
The owner should check this area regularly and report any suspicious conditions to the veterinarian immediately.
8. Spending Time and Care for Your Cat
FeLV-positive cats can be sensitive and emotional. Owner attention directly improves the cat's behavioral and psychological health.
FeLV in Cats: Differences Between Cats and Dogs
FeLV (Feline Leukemia Virus) is a retrovirus unique to cats, and no similar immune system cancer or retroviral infection exists in dogs. Therefore, both the biological behavior and clinical course of FeLV are uniquely tailored to the physiology of cats. These differences between cats and dogs are crucial to understanding FeLV.
1. Species Specificity
FeLV only infects cats ; it cannot be transmitted to dogs, humans, or other animals.
There is no retroviral leukemia disease similar to FeLV in dogs.
Therefore, all clinical effects of FeLV are specific to the feline immune system.
2. The Immune System Response Is Different
In cats, FeLV affects the immune system:
T-lymphocytes,
B-lymphocytes,
Bone marrow
direct pressures.
This pattern of viral suppression is not seen in dogs. Immunosuppression in dogs is more often due to chronic diseases, stress, or genetic immunodeficiency.
3. The Contagion Dynamics Are Completely Different
FeLV in cats is transmitted through:
Social contact (saliva, food and water bowl, licking)
Mother-offspring transmission
Blood contact
Common living area
There are no retroviral diseases transmitted through social contact in dogs. Certain viruses infect dogs, but none are similar in structure to FeLV.
4. Clinical Signs Only Appropriate to Cat Physiology
FeLV in cats:
Anemia
Lymphoma
Bone marrow suppression
Stomatitis
Chronic respiratory infections
Immune collapse
It creates symptoms such as. Most immune system diseases seen in dogs do not overlap with this picture.
5. Cancer Risk Profile Is Different
In cats, FeLV is particularly strongly associated with lymphoma and lymphosarcoma. Such tumors can be seen in dogs, but they are in no way linked to a viral trigger such as FeLV.
6. Diagnostic Methods Are Specific
FeLV tests such as ELISA, IFA and PCR have been developed exclusively for cats.
FeLV testing in dogs is meaningless.
This indicates that FeLV is a completely species-specific disease.
7. Treatment and Management Protocols Developed Exclusively for Cats
FeLV positive cats:
Oral care,
Infection control,
Nutritional order,
Blood count monitoring
It includes clinical protocols that are completely specific to cats. There is no type of viral leukemia in dogs that would require such a protocol.
Frequently Asked Questions (FAQ)
What is FeLV in cats and why is feline leukemia so dangerous?
FeLV is an aggressive retrovirus that directly affects cats' immune systems, bone marrow, and blood cells. The danger of the disease stems from the virus's ability to suppress the entire immune system, not just a single organ. In FeLV-positive cats, even simple infections can become severe when the immune system becomes ineffective. Complications such as anemia, lymphoma, chronic respiratory infections, stomatitis, weight loss, organ enlargements, and tumors can develop over time. FeLV doesn't directly kill the cat, but by destroying its immune system, it can pave the way for fatal infections.
How is FeLV transmitted in cats and why is it spread more easily than FIV?
FeLV is found in high concentrations in saliva, nasal discharge, blood, and other body fluids. Therefore, it can spread very easily among cats through social contact. Licking each other, sharing the same water bowl, and even sleeping in the same bed can lead to transmission. While FIV is most commonly transmitted through bites, FeLV can even be transmitted through social contact. Mother-to-kitten transmission is also common.
Can a FeLV-positive cat infect humans or dogs?
No. FeLV only infects cats. It is biologically impossible for it to be transmitted to humans, dogs, rabbits, or other animal species. There is no risk to other species living in the same household.
How long do FeLV positive cats live?
Life expectancy varies depending on the type of infection. In regressive infections, cats can live normally for 10–15 years . In progressive FeLV infection, life expectancy is between 2–5 years . However, with proper care, parasite protection, oral hygiene, a quality diet, stress management, and regular veterinary checkups, FeLV-positive cats can remain stable for many years.
Can FeLV-positive cats and healthy cats live in the same household?
This depends on the cats' behavior towards each other. Because FeLV is transmitted through saliva and social contact, harmonious, calm cats that don't fight can coexist. However, the risk isn't zero. To maintain a healthy cat, it's essential to keep food and water bowls separate, reduce the risk of fighting, and conduct regular testing.
What are the symptoms of FeLV and how do they progress?
FeLV symptoms often begin insidiously: mild fatigue, runny nose, recurring eye infections, gingivitis, and mild weight loss. As the virus progresses, serious clinical conditions such as anemia, enlarged lymph nodes, chronic stomatitis, persistent infections, respiratory distress, intestinal problems, and tumors emerge.
How is FeLV diagnosed? Which tests are reliable?
The first step in diagnosis is the rapid ELISA test. This test detects FeLV antigen in a blood sample. A positive result requires confirmation; at this stage, an IFA test or PCR test is used. PCR is the most sensitive method because it directly detects the virus's DNA/RNA. Both clinical symptoms and laboratory results should be evaluated together.
Is there a definitive treatment for FeLV positive cats?
No, there is no treatment that completely eradicates the virus. However, it is possible to control the infection. Treatment includes immune support (interferons, antioxidants), early treatment of secondary infections, stomatitis management, anemia treatment, and, if necessary, chemotherapy protocols. With proper care, many FeLV cats can live stable lives for long periods.
Can a FeLV positive cat fully recover?
A complete viral cure is impossible. However, in regressive FeLV infections, the virus can be suppressed, and the cat may not show any positivity for years. These cats can live healthy lives without any clinical signs.
What is the difference between FeLV and FIV?
FIV is most commonly transmitted through bites and progresses more slowly. FeLV spreads more rapidly through saliva and social contact. FeLV is also more strongly linked to blood cancers, tumors, and severe anemia. Immunosuppression is seen with both viruses, but FeLV generally produces a more aggressive clinical picture.
What should be considered when feeding FeLV positive cats?
Nutrition is one of the most critical components of FeLV management. High-quality protein-containing foods, wet food, Omega-3 supplements, antioxidants, and easily digestible ingredients are used. If the cat has a poor appetite, strongly flavored, soft foods can be preferred. Increasing water intake protects kidney health.
Why is stomatitis common in FeLV-positive cats?
A weakened immune system makes it difficult to fight oral bacteria. This leads to gingivitis, oral sores, pain, increased salivation, and bad breath. Stomatitis is one of the most severe complications of FeLV, and oral hygiene should never be neglected.
Can FeLV positive cats go outside?
Absolutely not. Going outdoors not only exposes cats to infection but also increases the risk of spreading the virus to other stray cats. FeLV-positive cats should always be kept indoors .
Does FeLV increase hair loss in cats?
Yes. In FeLV-positive cats, the coat becomes dull, lacks shine, and patchy hair loss may occur. This is due to immune suppression, nutritional deficiencies, and secondary skin infections.
What should a FeLV positive cat's living environment be like?
It should be quiet, clean, hygienic, and free from stress factors. Food and water bowls should be washed daily, and the litter box should be cleaned regularly. The cat should be provided with a dedicated resting area and a warm environment. Because stress lowers the immune system, a routine should be maintained.
Is it normal for a FeLV positive cat to lose weight?
Weight loss is one of the most common symptoms of FeLV. Cats can lose weight rapidly due to anemia, stomatitis, chronic infections, and metabolic stress. Veterinary care should be sought as soon as weight loss is noticed.
What is the risk of developing tumors in FeLV-positive cats?
FeLV plays a role in the development of cancers such as lymphoma and lymphosarcoma . The risk of lymphoma is significantly higher in FeLV-positive cats than in healthy cats. A mass in the chest cavity, enlarged lymph nodes in the abdomen, or intestinal tumors may be observed.
How does anemia occur in FeLV positive cats?
FeLV can affect the bone marrow, reducing red blood cell production. Additionally, immune system disorders can cause premature breakdown of red blood cells. Severe anemia manifests as pallor, weakness, rapid breathing, and collapse.
How do FeLV-positive cats infect other cats in the home?
The most common transmission is through saliva. Licking, sharing food and water bowls, nose-to-nose contact, and close social interaction facilitate transmission. Fighting, bites, and blood contact further increase the risk.
Why are eye and ear infections common in FeLV-positive cats?
Because the immune system is weakened, bacteria, yeast, and viruses that the body normally controls can proliferate rapidly. Discharge, redness, and conjunctivitis can occur in the eyes, and odor, wax buildup, and itching can occur in the ears.
What can be done to improve the quality of life of FeLV-positive cats?
Healthy eating
Regular oral care
Stress-free environment
Parasite control
Regular veterinary check-ups
Clean water and hygienic living space
Early infection treatmentAll these steps increase both the life expectancy and quality of life of FeLV-positive cats.
Does FeLV cause behavioral changes in cats?
It can. As the disease progresses, behavioral changes such as fatigue, depression, aggression, hiding, and loss of desire to play may occur. These are often related to general health.
Can FeLV positive cats be vaccinated?
Yes, but the vaccination protocol must be specifically designed by a veterinarian. Unnecessary vaccination should be avoided in FeLV-positive cats; only the necessary vaccines should be administered based on their lifestyle.
Sources
Cat Fanciers' Association (CFA)
The International Cat Association (TICA)
American Veterinary Medical Association (AVMA)
Mersin Vetlife Veterinary Clinic – Open on Map: https://share.google/XPP6L1V6c1EnGP3Oc




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